Welcome to the Klein Lab!

Our mission is to understand basic principles of the blood and immune system by studying rare human patients with inherited disorders. Our investigations start with the analysis of the patients phenotype, we unravel the genetic etiology of rare diseases and explore their pathomechanisms using a wide variety of in vitro and in vivo model systems. We aim to develop novel threapeutic strategies based on new insights into molecular mechanisms of disease. A particular focus is placed on cell and gene therapy.

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